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Recently, I install CircuitPython on ESP32-S3-DevKitC-1 on Ubuntu MATE 22.04 LTS/VirtualBox . But the CP2102N USB to UART Bridge Controller always attached and disconnected, like this: It's found that the interface 0 claimed by cp210x while 'brltty' sets config. BRLTTY is a background process (daemon) which provides access to the Linux/Unix console (when in text mode) for a blind person using a refreshable braille display. It drives the braille display, and provides complete screen review functionality. Some speech capability has also been incorporated. In my own case , I think brltty is not needed, so I remove it with command: sudo apt remove brltty It work for me, ttyUSB0 can be connected normally after brltty removed.

Geany is a lightweight programmer's text editor . To install geany on Ubuntu MATE, enter the command in Terminal: sudo apt install geany

This video show steps to install Arduino IDE 1.8.19 on Ubuntu MATE 22.04 LTS, and set permission for USB. Visit https://www.arduino.cc/en/software to download Arduino IDE 1.18.19, Linux 64 bits. Extract the downloaded file and run install.sh in terminal: sudo ./install.sh Normally, it will fail to upload due to permission denied. To fix it, enter the commands: sudo usermod -a -G dialout <user> sudo chmod a+rw <port> The Ubuntu MATE is installed over VirtualBox in last post , the video also show how to forward USB to virtual machine by adding to USB Device Filters. related: ~  Setup and post install Arduino IDE for Nano RP2040 Connect, on Ubuntu MATE ~  Check if I belongs to dialout group

Visit https://ubuntu-mate.org/download/ to download 64-bit PCs/Macs 22.04 LTS. It's strongly recpmmended to install Guest Additions CD image, as shown in the video.